Permanent Hair Dye (Oxidative) — safety profile
Elevated riskPermanent oxidative hair dyes using p-phenylenediamine (PPD) or p-aminophenol as primary intermediates, hydrogen peroxide as developer, and ammonia or ethanolamine as alkalizer.
What is this product?
Permanent oxidative hair dyes using p-phenylenediamine (PPD) or p-aminophenol as primary intermediates, hydrogen peroxide as developer, and ammonia or ethanolamine as alkalizer. PPD is the most common cause of allergic contact dermatitis from cosmetics. IARC classifies occupational exposure to hair dyes as 'probably carcinogenic' (Group 2A) — personal use classified as Group 3 (not classifiable).
What's in it
Click any compound name for its full safety profile, regulatory consensus, and exposure data.
Intermediate
Alkalizer
Developer
Red flags — when to walk away
- Product causes skin irritation, redness, or rash — Contact dermatitis or chemical sensitivity.
Green flags — what to look for
- EWG Verified or dermatologist-tested label — Meets strict ingredient safety criteria.
Safer alternatives
- Semi-permanent dye — no ammonia, no developer, lower PPD
- Henna — plant-based, no synthetic chemicals — limited color range
- PPD-free permanent dyes — use ME-PPD or PTD alternatives
Frequently asked questions
Are there safer alternatives to Permanent Hair Dye (Oxidative)?
Yes — consider: Semi-permanent dye; Henna; PPD-free permanent dyes. See the Safer alternatives section above for details.
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Open in body View raw API dataReference data, not professional advice. Aggregates publicly available regulatory and scientific information. Why we built ALETHEIA →