BPA Dental Sealants — Bisphenol A Leaching from Bis-GMA Resin, Pediatric Endocrine Disruption Concern (Pit-and-Fissure Sealants, Saliva BPA Levels) — safety profile
Low riskDental pit-and-fissure sealants are resin coatings applied to the occlusal surfaces of children's permanent molars to prevent caries — one of the most effective preventive dental interventions, reducing caries by 80% in the first 2 years (Cochrane review).
What is this product?
Dental pit-and-fissure sealants are resin coatings applied to the occlusal surfaces of children's permanent molars to prevent caries — one of the most effective preventive dental interventions, reducing caries by 80% in the first 2 years (Cochrane review). The vast majority of sealants are based on Bis-GMA (bisphenol A glycidyl methacrylate), synthesized from bisphenol A (BPA). BPA leaches from sealants into saliva, with studies detecting salivary BPA concentrations of 5-30 ng/mL in the first hour after placement, declining to baseline within 24 hours as the surface monomer layer is consumed. The concern is pediatric endocrine disruption: BPA is an established estrogen receptor agonist, and children receiving sealants are typically 6-12 years old (permanent molar eruption age). A 2012 study in Pediatrics associated dental sealants with increased BPA exposure, though the clinical significance of transient salivary BPA from sealants versus continuous dietary BPA exposure remains debated. The ADA continues to recommend sealants, noting the caries-prevention benefit substantially outweighs the minimal, transient BPA exposure.
What's in it
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Leachable Monomer
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