Body & Beauty / Compounds / Trichophyton rubrum

Trichophyton rubrum on your skin: a safety profile

Low risk

(People-specific data is limited; this page draws from human adult context.) Trichophyton rubrum is the most common dermatophyte worldwide, responsible for an estimated 69-70% of all dermatophyte infections. It causes tinea pedis (athlete's foot), tinea cruris (jock itch), tinea corporis (ringworm), and tinea unguium (onychomycosis/fungal nail infection). Global prevalence of superficial fungal infections: 20-25% of the world population, making dermatophytosis one of the most common infectious diseases. T. rubrum is an anthropophilic species (human-adapted) that produces minimal inflammatory response compared to zoophilic dermatophytes, allowing chronic, persistent infections. Virulence factors: secreted proteases (keratinases, subtilisins) that degrade keratin in skin, hair, and nails. Infection is superficial (stratum corneum) and does not invade living tissue in immunocompetent hosts — deep dermatophytosis is extremely rare and occurs only in profound immunodeficiency. Treatment: topical azoles or terbinafine for skin infections; oral terbinafine or itraconazole for nail infections (12-week course, 70-80% cure rate). Terbinafine-resistant T. rubrum has been reported but remains uncommon. Economic burden is significant: onychomycosis alone costs >$1 billion/year in the US.

What is trichophyton rubrum?

Risk for people

Low risk

Trichophyton rubrum is the most common dermatophyte worldwide, responsible for an estimated 69-70% of all dermatophyte infections. It causes tinea pedis (athlete's foot), tinea cruris (jock itch), tinea corporis (ringworm), and tinea unguium (onychomycosis/fungal nail infection). Global prevalence of superficial fungal infections: 20-25% of the world population, making dermatophytosis one of the most common infectious diseases. T. rubrum is an anthropophilic species (human-adapted) that produces minimal inflammatory response compared to zoophilic dermatophytes, allowing chronic, persistent infections. Virulence factors: secreted proteases (keratinases, subtilisins) that degrade keratin in skin, hair, and nails. Infection is superficial (stratum corneum) and does not invade living tissue in immunocompetent hosts — deep dermatophytosis is extremely rare and occurs only in profound immunodeficiency. Treatment: topical azoles or terbinafine for skin infections; oral terbinafine or itraconazole for nail infections (12-week course, 70-80% cure rate). Terbinafine-resistant T. rubrum has been reported but remains uncommon. Economic burden is significant: onychomycosis alone costs >$1 billion/year in the US.

Regulatory consensus

1 regulatory bodyhas classified Trichophyton rubrum.

AgencyYearClassificationNotes
Unknown

Regulators apply different standards of evidence — animal-data weighting, exposure-pattern assumptions, epidemiological power thresholds — which is why two scientific bodies can review the same data and reach different conclusions. The disagreement is the data.

Where you encounter trichophyton rubrum

  • Human Skin And NailsFeet (athlete's foot), Toenails (onychomycosis), Groin (jock itch)
  • FomitesShower floors, Locker rooms, Shared footwear, Nail salons

Frequently asked questions

What products contain trichophyton rubrum?

Trichophyton rubrum appears in: Feet (athlete's foot) (Human skin and nails); Toenails (onychomycosis) (Human skin and nails); Shower floors (Fomites); Locker rooms (Fomites).

See Trichophyton rubrum in the body app

Look up products containing trichophyton rubrum, compare to alternatives, and explore the full data record.

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Sources (2)

  1. PubChem (2026) — database
  2. ALETHEIA fungi compound batch (2026) — batch_creation

Reference data, not professional advice. Aggregates publicly available regulatory and scientific data; not a substitute for veterinary, medical, legal, or regulatory advice. Why we built ALETHEIA →