Traseolide on your skin: a safety profile

What is traseolide?

The IUPAC name is 1-[(2R,3R)-1,1,2,6-tetramethyl-3-propan-2-yl-2,3-dihydroinden-5-yl]ethanone.

Also known as: BB_NC-00275, PDA90FUN2J, 68857-95-4, Ethanone, 1-(2,3-dihydro-1,1,2,6-tetramethyl-3-(1-methylethyl)-1H-inden-5-yl)-, trans-.

IUPAC name

1-[(2R,3R)-1,1,2,6-tetramethyl-3-propan-2-yl-2,3-dihydroinden-5-yl]ethanone

CAS number

68140-48-7

Molecular formula

C17H24O

Molecular weight

244.37 g/mol

SMILES

C[C@@H]1[C@H](C2=C(C1(C)C)C=C(C(=C2)C(=O)C)C)C(C)C

PubChem CID

50256

Regulatory consensus

1 regulatory bodyhas classified Traseolide.

Regulators apply different standards of evidence — animal-data weighting, exposure-pattern assumptions, epidemiological power thresholds — which is why two scientific bodies can review the same data and reach different conclusions. The disagreement is the data.

Where you encounter traseolide

• Personal Care — perfume, soap, cosmetics
• Consumer Products — cleaning products, candles

Safer alternatives

Lower-risk approaches that achieve a similar outcome to Traseolide:

• Lower-sensitization structural analog; Unscented formulation
  Trade-offs: Eliminates allergen risk entirely; consumer acceptance varies (some associate scent with cleanliness/efficacy); growing market segment; regulatory advantage in EU (no IFRA compliance needed).
  Relative cost: 1.2-2×

Frequently asked questions