trans-Anethole on your skin: a safety profile
Context-dependentSafety profile for trans-Anethole relevant to people.
What is trans-anethole?
Also known as: ANETHOLE, Anise camphor, Monasirup, Anethol.
- CAS number
- 4180-23-8
- Molecular formula
- C10H12O
- Molecular weight
- 148.20 g/mol
- SMILES
- CC=CC1=CC=C(C=C1)OC
- PubChem CID
- 637563
Risk for people
Context-dependentRegulatory consensus
1 regulatory bodyhas classified trans-Anethole.
| Agency | Year | Classification | Notes |
|---|---|---|---|
| EDC Assessment | — | Suspected endocrine disruptor |
Regulators apply different standards of evidence — animal-data weighting, exposure-pattern assumptions, epidemiological power thresholds — which is why two scientific bodies can review the same data and reach different conclusions. The disagreement is the data.
Where you encounter trans-anethole
- Personal Care — perfume, soap, cosmetics
- Consumer Products — cleaning products, candles
Safer alternatives
Lower-risk approaches that achieve a similar outcome to trans-Anethole:
-
Lower-sensitization structural analog; Unscented formulation
Trade-offs: Eliminates allergen risk entirely; consumer acceptance varies (some associate scent with cleanliness/efficacy); growing market segment; regulatory advantage in EU (no IFRA compliance needed).Relative cost: 1.2-2×
Frequently asked questions
What products contain trans-anethole?
trans-Anethole appears in: perfume (Personal care); soap (Personal care); cleaning products (Consumer products); candles (Consumer products).
See trans-Anethole in the body app
Look up products containing trans-anethole, compare to alternatives, and explore the full data record.
Open in body View raw API dataSources (1)
- PubChem (2026) — database
Reference data, not professional advice. Aggregates publicly available regulatory and scientific data; not a substitute for veterinary, medical, legal, or regulatory advice. Why we built ALETHEIA →