Body & Beauty / Compounds / Tocopheryl acetate (Vitamin E acetate)

Tocopheryl acetate (Vitamin E acetate) on your skin: a safety profile

Low risk

Not medical or professional safety advice, and not a substitute for a qualified clinician — consult one. Full disclaimer →

(People-specific data is limited; this page draws from human adult context.) Generally safe dermally/orally; EVALI (vaping lung injury) when inhaled as oil in THC vapes — not relevant to cosmetic/supplement use; rare contact dermatitis

What is tocopheryl acetate (vitamin e acetate)?

The IUPAC name is [(2R)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydrochromen-6-yl] acetate.

Also known as: BBL027614, |A-Tocopherol; All-Rac-|A-Tocopherol, T0251, DL-α-tocopherol.

IUPAC name
[(2R)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydrochromen-6-yl] acetate
CAS number
10191-41-0
Molecular formula
C29H50O2
Molecular weight
430.7 g/mol
SMILES
CC1=C(C(=C(C2=C1O[C@](CC2)(C)CCC[C@H](C)CCC[C@H](C)CCCC(C)C)C)OC(=O)C)C
PubChem CID
86472

Risk for people

Low risk

Generally safe dermally/orally; EVALI (vaping lung injury) when inhaled as oil in THC vapes — not relevant to cosmetic/supplement use; rare contact dermatitis

Regulatory consensus

1 regulatory bodyhas classified Tocopheryl acetate (Vitamin E acetate).

AgencyYearClassificationNotes
US FDA—Regulated under dietary supplement frameworks (DSHEA in US, EU Novel Food)

Regulators apply different standards of evidence — animal-data weighting, exposure-pattern assumptions, epidemiological power thresholds — which is why two scientific bodies can review the same data and reach different conclusions. The disagreement is the data.

Where you encounter tocopheryl acetate (vitamin e acetate)

  • Personal Care — moisturizer, sunscreen, lip balm, baby products, shampoo
  • Consumer Products — dietary supplements

Safer alternatives

Lower-risk approaches that achieve a similar outcome to Tocopheryl acetate (Vitamin E acetate):

  • Food-based nutrient sources; Whole food diet
    Trade-offs: Alternative approach; specific tradeoffs depend on application context, scale, and regulatory requirements. Full hazard assessment of alternative recommended before adoption to avoid regrettable substitution.
    Relative cost: 1.2-2×

Frequently asked questions

What products contain tocopheryl acetate (vitamin e acetate)?

Tocopheryl acetate (Vitamin E acetate) appears in: moisturizer (Personal care); sunscreen (Personal care); dietary supplements (Consumer products).

See Tocopheryl acetate (Vitamin E acetate) in the body app

Look up products containing tocopheryl acetate (vitamin e acetate), compare to alternatives, and explore the full data record.

Open in body View raw API data

Sources (1)
  1. PubChem Compound Database (2026) — database

Reference data, not professional advice. Aggregates publicly available regulatory and scientific data; not a substitute for medical, legal, or regulatory advice. Why we built ALETHEIA →