Body & Beauty / Compounds / Hedione (methyl dihydrojasmonate)

Hedione (methyl dihydrojasmonate) on your skin: a safety profile

Low risk

(People-specific data is limited; this page draws from human adult context.) Fragrance terpene ester/alcohol — generally low toxicity; some members are EU designated allergens (cinnamyl alcohol, citronellol); oxidation products may be more allergenic than parent compound

What is hedione (methyl dihydrojasmonate)?

The IUPAC name is methyl 2-(3-oxo-2-pentylcyclopentyl)acetate.

Also known as: methyl 2-(3-oxo-2-pentylcyclopentyl)acetate, Methyl dihydrojasmonate, Hedione, Kharismal.

IUPAC name
methyl 2-(3-oxo-2-pentylcyclopentyl)acetate
CAS number
24851-98-7
Molecular formula
C13H22O3
Molecular weight
226.31 g/mol
SMILES
CCCCCC1C(CCC1=O)CC(=O)OC
PubChem CID
102861

Risk for people

Low risk

Fragrance terpene ester/alcohol — generally low toxicity; some members are EU designated allergens (cinnamyl alcohol, citronellol); oxidation products may be more allergenic than parent compound

Regulatory consensus

1 regulatory bodyhas classified Hedione (methyl dihydrojasmonate).

AgencyYearClassificationNotes
IFRA2024no_restrictionNo IFRA restriction.

Regulators apply different standards of evidence — animal-data weighting, exposure-pattern assumptions, epidemiological power thresholds — which is why two scientific bodies can review the same data and reach different conclusions. The disagreement is the data.

Where you encounter hedione (methyl dihydrojasmonate)

  • Personal Careperfume, soap, lotion, shampoo
  • Consumer Productscleaning products, air fresheners
  • Fragranceperfume, cologne, scented personal care products, household fragrance products, candles
    Identified in Fragrance Ingredient Safety Priority Research database (2,325 ingredients)

Safer alternatives

Lower-risk approaches that achieve a similar outcome to Hedione (methyl dihydrojasmonate):

  • Paradisone
    Trade-offs: Alternative fragrance ingredient; individual safety profile should be assessed per IFRA standards; sensitization potential varies by compound; patch testing recommended for sensitive individuals.
    Relative cost: 1.2-2×
  • Methyl jasmonate
    Trade-offs: Alternative fragrance ingredient; individual safety profile should be assessed per IFRA standards; sensitization potential varies by compound; patch testing recommended for sensitive individuals.
    Relative cost: 1.2-2×

Frequently asked questions

What products contain hedione (methyl dihydrojasmonate)?

Hedione (methyl dihydrojasmonate) appears in: perfume (Personal care); soap (Personal care); cleaning products (Consumer products); air fresheners (Consumer products); perfume (Fragrance).

See Hedione (methyl dihydrojasmonate) in the body app

Look up products containing hedione (methyl dihydrojasmonate), compare to alternatives, and explore the full data record.

Open in body View raw API data

Sources (1)

  1. PubChem Compound Database (2026) — database

Reference data, not professional advice. Aggregates publicly available regulatory and scientific data; not a substitute for veterinary, medical, legal, or regulatory advice. Why we built ALETHEIA →