Hedione (methyl dihydrojasmonate) on your skin: a safety profile
Low risk(People-specific data is limited; this page draws from human adult context.) Fragrance terpene ester/alcohol — generally low toxicity; some members are EU designated allergens (cinnamyl alcohol, citronellol); oxidation products may be more allergenic than parent compound
What is hedione (methyl dihydrojasmonate)?
The IUPAC name is methyl 2-(3-oxo-2-pentylcyclopentyl)acetate.
Also known as: methyl 2-(3-oxo-2-pentylcyclopentyl)acetate, Methyl dihydrojasmonate, Hedione, Kharismal.
- IUPAC name
- methyl 2-(3-oxo-2-pentylcyclopentyl)acetate
- CAS number
- 24851-98-7
- Molecular formula
- C13H22O3
- Molecular weight
- 226.31 g/mol
- SMILES
- CCCCCC1C(CCC1=O)CC(=O)OC
- PubChem CID
- 102861
Risk for people
Low riskFragrance terpene ester/alcohol — generally low toxicity; some members are EU designated allergens (cinnamyl alcohol, citronellol); oxidation products may be more allergenic than parent compound
Regulatory consensus
1 regulatory bodyhas classified Hedione (methyl dihydrojasmonate).
| Agency | Year | Classification | Notes |
|---|---|---|---|
| IFRA | 2024 | no_restriction | No IFRA restriction. |
Regulators apply different standards of evidence — animal-data weighting, exposure-pattern assumptions, epidemiological power thresholds — which is why two scientific bodies can review the same data and reach different conclusions. The disagreement is the data.
Where you encounter hedione (methyl dihydrojasmonate)
- Personal Care — perfume, soap, lotion, shampoo
- Consumer Products — cleaning products, air fresheners
-
Fragrance
— perfume, cologne, scented personal care products, household fragrance products, candles
Identified in Fragrance Ingredient Safety Priority Research database (2,325 ingredients)
Safer alternatives
Lower-risk approaches that achieve a similar outcome to Hedione (methyl dihydrojasmonate):
-
Paradisone
Trade-offs: Alternative fragrance ingredient; individual safety profile should be assessed per IFRA standards; sensitization potential varies by compound; patch testing recommended for sensitive individuals.Relative cost: 1.2-2×
-
Methyl jasmonate
Trade-offs: Alternative fragrance ingredient; individual safety profile should be assessed per IFRA standards; sensitization potential varies by compound; patch testing recommended for sensitive individuals.Relative cost: 1.2-2×
Frequently asked questions
What products contain hedione (methyl dihydrojasmonate)?
Hedione (methyl dihydrojasmonate) appears in: perfume (Personal care); soap (Personal care); cleaning products (Consumer products); air fresheners (Consumer products); perfume (Fragrance).
See Hedione (methyl dihydrojasmonate) in the body app
Look up products containing hedione (methyl dihydrojasmonate), compare to alternatives, and explore the full data record.
Open in body View raw API dataSources (1)
- PubChem Compound Database (2026) — database
Reference data, not professional advice. Aggregates publicly available regulatory and scientific data; not a substitute for veterinary, medical, legal, or regulatory advice. Why we built ALETHEIA →