Dicaprylyl carbonate on your skin: a safety profile

What is dicaprylyl carbonate?

Also known as: caprylic carbonic ester, 8-1 carbonate, 5-METHYLINDOLE, KT52363RI5.

IUPAC name

dicaprylyl carbonate

CAS number

1680-31-5

Molecular formula

C17H34O3

Molecular weight

286.46 g/mol

SMILES

CC1=CC2=C(C=C1)NC=C2

PubChem CID

11978

Regulatory consensus

2 regulatory and scientific bodies have classified Dicaprylyl carbonate. The classifications differ — that's the data.

Regulators apply different standards of evidence — animal-data weighting, exposure-pattern assumptions, epidemiological power thresholds — which is why two scientific bodies can review the same data and reach different conclusions. The disagreement is the data.

Where you encounter dicaprylyl carbonate

• facial_serum
• lightweight_moisturizer
• premium_sunscreen
• color_cosmetics

Safer alternatives

Lower-risk approaches that achieve a similar outcome to Dicaprylyl carbonate:

• Plant-derived oils with established safety profiles (jojoba, squalane, shea butter)
  Trade-offs: Consumer preference for 'natural' label; many natural fragrance compounds are potent allergens (limonene, linalool, eugenol); 'natural' ≠ 'safe'; often more expensive than synthetic equivalents.
  Relative cost: 2-5× conventional
• Ceramide-based formulations (biomimetic skin barrier repair)
  Trade-offs: Alternative emollient; skin feel, spreadability, and occlusion properties differ; comedogenicity should be assessed for facial use; stability in final formulation needs verification.
  Relative cost: 1.2-2×
• Glycerin-based humectant systems as partial replacement
  Trade-offs: Direct chemical substitution requires verification that the replacement does not introduce new hazards (regrettable substitution). Conduct full hazard assessment of proposed alternative before adoption.
  Relative cost: 1.2-2×

Frequently asked questions