Body & Beauty / Compounds / beta-Caryophyllene

beta-Caryophyllene on your skin: a safety profile

Context-dependent

Safety profile for beta-Caryophyllene relevant to people.

What is beta-caryophyllene?

Also known as: Caryophyllene, (-)-trans-Caryophyllene, L-Caryophyllene, trans-beta-caryophyllene.

CAS number
87-44-5
Molecular formula
C15H24
Molecular weight
204.35 g/mol
SMILES
CC1=CCCC(=C)C2CC(C2CC1)(C)C
PubChem CID
5281515

Risk for people

Context-dependent

Regulatory consensus

1 regulatory bodyhas classified beta-Caryophyllene.

AgencyYearClassificationNotes
Unknown——

Regulators apply different standards of evidence — animal-data weighting, exposure-pattern assumptions, epidemiological power thresholds — which is why two scientific bodies can review the same data and reach different conclusions. The disagreement is the data.

Where you encounter beta-caryophyllene

  • Personal Care — perfume, soap, cosmetics
  • Consumer Products — cleaning products, candles

Safer alternatives

Lower-risk approaches that achieve a similar outcome to beta-Caryophyllene:

  • Lower-sensitization structural analog; Unscented formulation
    Trade-offs: Eliminates allergen risk entirely; consumer acceptance varies (some associate scent with cleanliness/efficacy); growing market segment; regulatory advantage in EU (no IFRA compliance needed).
    Relative cost: 1.2-2×

Frequently asked questions

What products contain beta-caryophyllene?

beta-Caryophyllene appears in: perfume (Personal care); soap (Personal care); cleaning products (Consumer products); candles (Consumer products).

See beta-Caryophyllene in the body app

Look up products containing beta-caryophyllene, compare to alternatives, and explore the full data record.

Open in body View raw API data

Sources (1)
  1. PubChem (2026) — database

Reference data, not professional advice. Aggregates publicly available regulatory and scientific data; not a substitute for veterinary, medical, legal, or regulatory advice. Why we built ALETHEIA →