Anisyl alcohol (4-methoxybenzyl alcohol) on your skin: a safety profile
Low risk(People-specific data is limited; this page draws from human adult context.) Fragrance terpene ester/alcohol — generally low toxicity; some members are EU designated allergens (cinnamyl alcohol, citronellol); oxidation products may be more allergenic than parent compound
What is anisyl alcohol (4-methoxybenzyl alcohol)?
The IUPAC name is (4-methoxyphenyl)methanol.
Also known as: (4-methoxyphenyl)methanol, 4-METHOXYBENZYL ALCOHOL, Anise alcohol, Anisyl alcohol.
- IUPAC name
- (4-methoxyphenyl)methanol
- CAS number
- 105-13-5
- Molecular formula
- C8H10O2
- Molecular weight
- 138.16 g/mol
- SMILES
- COC1=CC=C(C=C1)CO
- PubChem CID
- 7738
Risk for people
Low riskFragrance terpene ester/alcohol — generally low toxicity; some members are EU designated allergens (cinnamyl alcohol, citronellol); oxidation products may be more allergenic than parent compound
Regulatory consensus
2 regulatory and scientific bodies have classified Anisyl alcohol (4-methoxybenzyl alcohol). The classifications differ — that's the data.
| Agency | Year | Classification | Notes |
|---|---|---|---|
| IFRA | 2024 | restriction | IFRA 51st Amendment — concentration limits |
| EU_COSMETICS | 2023 | allergen_disclosure | EU Reg 2023/1545 — expanded allergen list |
Regulators apply different standards of evidence — animal-data weighting, exposure-pattern assumptions, epidemiological power thresholds — which is why two scientific bodies can review the same data and reach different conclusions. The disagreement is the data.
Where you encounter anisyl alcohol (4-methoxybenzyl alcohol)
- Personal Care — perfume, soap, lotion, shampoo
- Consumer Products — cleaning products, air fresheners
-
Fragrance
— perfume, cologne, scented personal care products, household fragrance products, candles
Identified in Fragrance Ingredient Safety Priority Research database (2,325 ingredients)
Safer alternatives
Lower-risk approaches that achieve a similar outcome to Anisyl alcohol (4-methoxybenzyl alcohol):
-
Phenylethyl alcohol
Trade-offs: Alternative fragrance ingredient; individual safety profile should be assessed per IFRA standards; sensitization potential varies by compound; patch testing recommended for sensitive individuals.Relative cost: 1.2-2×
-
Benzyl alcohol
Trade-offs: Alternative fragrance ingredient; individual safety profile should be assessed per IFRA standards; sensitization potential varies by compound; patch testing recommended for sensitive individuals.Relative cost: 1.2-2×
Frequently asked questions
What products contain anisyl alcohol (4-methoxybenzyl alcohol)?
Anisyl alcohol (4-methoxybenzyl alcohol) appears in: perfume (Personal care); soap (Personal care); cleaning products (Consumer products); air fresheners (Consumer products); perfume (Fragrance).
See Anisyl alcohol (4-methoxybenzyl alcohol) in the body app
Look up products containing anisyl alcohol (4-methoxybenzyl alcohol), compare to alternatives, and explore the full data record.
Open in body View raw API dataSources (1)
- PubChem Compound Database (2026) — database
Reference data, not professional advice. Aggregates publicly available regulatory and scientific data; not a substitute for veterinary, medical, legal, or regulatory advice. Why we built ALETHEIA →